USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P18085 USC-OGP 2-DE database:  P18085 P18085 General information about the entry View entry in simple text format Entry name ARF4_HUMAN Primary accession number P18085 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=ADP-ribosylation factor 4;. Gene name Name=ARF4 Synonyms=ARF2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1316: pI=6.18; Mw=19834 SPOT OGP-1331: pI=5.13; Mw=16684 Cross-references UniProtKB/Swiss-Prot P18085; ARF4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ARF4_HUMAN Primary accession number P18085 Secondary accession number(s) B2R7J7 P21371 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 181) Name and origin of the protein Description RecName: Full=ADP-ribosylation factor 4; Gene name Name=ARF4 Synonyms=ARF2 Encoded on Name=ARF4; Synonyms=ARF2 Keywords 3D-structure; Complete proteome; ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Myristate; Nucleotide-binding; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M36341; AAA53081.1; -; mRNA EMBL AF104238; AAD54674.1; -; Genomic_DNA EMBL AF104233; AAD54674.1; JOINED; Genomic_DNA EMBL AF104234; AAD54674.1; JOINED; Genomic_DNA EMBL AF104235; AAD54674.1; JOINED; Genomic_DNA EMBL AF104236; AAD54674.1; JOINED; Genomic_DNA EMBL AF104237; AAD54674.1; JOINED; Genomic_DNA EMBL AF493883; AAM12597.1; -; mRNA EMBL AK313008; BAG35844.1; -; mRNA EMBL BC003364; AAH03364.1; -; mRNA EMBL BC008753; AAH08753.1; -; mRNA EMBL BC016325; AAH16325.1; -; mRNA EMBL BC022866; AAH22866.1; -; mRNA CCDS CCDS2884.1; -; . PIR B38622; B38622; . RefSeq NP_001651.1; NM_001660.3; . UniGene Hs.652183; -; . PDB 1Z6X; X-ray; 2.70 A; A/B=1-180 PDBsum 1Z6X; -; . ProteinModelPortal P18085; -; . SMR P18085; -; . BioGrid 106873; 47; . DIP DIP-38214N; -; . IntAct P18085; 13; . MINT MINT-2801449; -; . STRING 9606.ENSP00000306010; -; . DrugBank DB04315; Guanosine-5'-Diphosphate; . iPTMnet P18085; -; . PhosphoSitePlus P18085; -; . SwissPalm P18085; -; . BioMuta ARF4; -; . DMDM 114123; -; . EPD P18085; -; . MaxQB P18085; -; . PaxDb P18085; -; . PeptideAtlas P18085; -; . PRIDE P18085; -; . TopDownProteomics P18085; -; . DNASU 378; -; . Ensembl ENST00000303436; ENSP00000306010; ENSG00000168374; . GeneID 378; -; . KEGG hsa:378; -; . UCSC uc003dix.5; human; . CTD 378; -; . DisGeNET 378; -; . GeneCards ARF4; -; . HGNC HGNC:655; ARF4; . MIM 601177; gene; . neXtProt NX_P18085; -; . OpenTargets ENSG00000168374; -; . PharmGKB PA24937; -; . eggNOG KOG0070; Eukaryota; . eggNOG COG1100; LUCA; . GeneTree ENSGT00780000121855; -; . HOGENOM HOG000163691; -; . HOVERGEN HBG002073; -; . InParanoid P18085; -; . KO K07939; -; . OMA WASSEIF; -; . OrthoDB EOG091G0S7S; -; . PhylomeDB P18085; -; . TreeFam TF300808; -; . Reactome R-HSA-5620916; VxPx cargo-targeting to cilium; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811434; COPI-dependent Golgi-to-ER retrograde traffic; . ChiTaRS ARF4; human; . EvolutionaryTrace P18085; -; . GeneWiki ARF4; -; . GenomeRNAi 378; -; . PRO PR:P18085; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000168374; -; . CleanEx HS_ARF4; -; . ExpressionAtlas P18085; baseline and differential; . Genevisible P18085; HS; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0043197; C:dendritic spine; IDA:MGI; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0032587; C:ruffle membrane; IDA:UniProtKB; . GO GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:Reactome; . GO GO:0005154; F:epidermal growth factor receptor binding; IDA:UniProtKB; . GO GO:0005525; F:GTP binding; IDA:UniProtKB; . GO GO:0003924; F:GTPase activity; TAS:Reactome; . GO GO:0031584; P:activation of phospholipase D activity; IDA:UniProtKB; . GO GO:0045176; P:apical protein localization; IEA:Ensembl; . GO GO:0007420; P:brain development; IEA:Ensembl; . GO GO:0016477; P:cell migration; IDA:UniProtKB; . GO GO:0060996; P:dendritic spine development; IDA:MGI; . GO GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl; . GO GO:0007612; P:learning; IEA:Ensembl; . GO GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB; . GO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB; . GO GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB; . GO GO:0061512; P:protein localization to cilium; IEA:Ensembl; . GO GO:0015031; P:protein transport; IEA:UniProtKB-KW; . GO GO:2000377; P:regulation of reactive oxygen species metabolic process; IDA:UniProtKB; . GO GO:0048678; P:response to axon injury; IEA:Ensembl; . GO GO:0006890; P:retrograde vesicle-mediated transport; Golgi to ER; IGI:WormBase GO GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro; . Gene3D 3.40.50.300; -; 1; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR005225; Small_GTP-bd_dom; . InterPro IPR024156; Small_GTPase_ARF; . InterPro IPR006689; Small_GTPase_ARF/SAR; . Pfam PF00025; Arf; 1; . PRINTS PR00328; SAR1GTPBP; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00231; small_GTP; 1; . PROSITE PS51417; ARF; 1; .

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